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Publications
Richard A. Perugini, M.D.
Fellow in Advanced Minimally Invasive Surgery
University of Massachusetts Medical Center

BIBLIOGRAPHY:

Perugini, RA, Orr, RK, Porter, D, Dumas, EM, Maini, BS.  “Gastrointestinal Complications Following Cardiac Surgery:  An Analysis of 1477 Cardiac Surgery Patients.”  Archives of Surgery 132(4):352-357  (1997). Perugini, RA, McDade, TP, Vittimberga, FJ, Callery, MP.  “The Molecular and Cellular Biology of Pancreatic Cancer.”  Critical Reviews in Eukaryotic Gene Expression 8(3&4):377-393  (1998). McDade, TP, Perugini, RA, Vittimberga, F, Carrigan, RC, Callery, MP.  “Salicylates inhibit NF-kappaB activation and enhance TNF-a-induced apoptosis in BxPC3 human pancreatic cancer cells.” Journal of Surgical Research 83:56-61 (1999). Vittimberga, FJ, McDade, TP, Perugini, RA, Callery, MP.  Sodium salicylates inhibits macrophage TNF-a production and alters MAPK activation.  Journal of Surgical Research 84(2):143-149 (1999). McDade, TP, Perugini, RA, Vittimberga, FJ, Carrigan, RC, Callery, MP.  “Ubiquitin proteasome inhibition enhances apoptosis of human pancreatic cancer cells.” Surgery 126(2):371-377 (1999). Perugini, RA, McDade, TP, Vittimberga, FJ, Callery, MP.  “Sodium salicylate inhibits proliferation and induces G1 cell cycle arrest in human pancreatic cancer.” Journal of Gastrointestinal Surgery 4(1):24-32 (2000). Perugini, RA, and Callery, MP.  “Complications of Laparoscopic Surgery” in Evidence Based Surgery.  Editors A.Fingerhut and Rene Holzheimer.  Springer-Verlag:  Heidelberg. 2001. Vittimberga, FJ, Nolan, BW, Perugini, RA, Spector, L, Callery, MP.  “Laparoscopic surgery and Kupffer cell activation.  Surgical Endoscopy 14(12):1171-1176 (2000). Perugini, RA, McDade, TP, Vittimberga, FJ, Callery, MP.  “Human pancreatic cancer cell proliferation is phosphatidylinositol 3-kinase (PI3K)-dependent.” Journal of Surgical Research 90(1):39-44 (2000). Ricciardi, R, Kim, R, McDade, TP, Perugini, RA, Veal, TM, Quarfordt, SH, Callery, MP, Chari, RS, Meyers, WC.  “NF-kB expression during cold ischemia correlates with post reperfusion graft function.”  Journal of Surgical Research 93(1):35-40 (2000). Shah, S, Potter, MW, Ricciardi, R, Perugini, RA, Callery, MP.  “FRAP-p70s6K signaling is required for pancreatic cancer cell proliferation.”  Journal of Surgical Research 97(2):123-130 (2001). Presentations Perugini, RA, Orr, RK, Porter, D, Dumas, EM, Maini, BS.  “Gastrointestinal Complications Following Cardiac Surgery:  An analysis of 1477 cardiac surgery patients.” Oral presentation at the 77th annual meeting of the New England Surgical Society, Dixville Notch, NH September 27-29, 1996. Vittimberga, FJ, Perugini, RA, Carrigan, RC, Callery, MP.  “Protein kinase C-z is required for Tumor Necrosis Factor-alpha production in lipopolysaccharide stimulated macrophages.”  Poster presentation at the 18th Annual Meeting of the Surgical Infection Society, New York, NY  April 30-May 2, 1998. McDade, TP, Perugini, RA, Vittimberga, FJ, Carrigan, RC, Callery, MP.  “Sodium salicylate inhibits Tumor Necrosis Factor-alpha induced IkBa phosphorylation and degradation in human pancreatic cancer.” Oral presentation at 1998 Surgical Forum, 84th Clinical Congress of the American College of Surgeons, Orlando, FL  October 25-30, 1998. Vittimberga, FJ, Perugini, RA, McDade, TP, Carrigan, RC, Callery, MP.  “Sodium salicylate inhibits TNF-a production in lipopolysaccharide stimulated macrophages.”  Oral presentation at 1998 Surgical Forum, 84th Clinical Congress of the American College of Surgeons, Orlando, FL  October 25-30, 1998.                 Vittimberga, FJ, McDade, TP, Perugini, RA, Carrigan, R, Callery, MP.  “Salicylates inhibit ERK1/ERK2 activation in endotoxin (LPS)-stimulated macrophages.”  Oral presentation at the Association of Academic Surgery 32nd Annual Meeting, Seattle, WA.  November 19-22, 1998.             McDade, TP, Perugini, RA, Vittimberga, F, Carrigan, RC, Callery, MP.  “Salicylates enhance TNF-a-induced apoptosis in BxPC3 human pancreatic cancer cells.” Oral presentation at the Association of Academic Surgery 32nd Annual Meeting, Seattle, WA  November 19-22, 1998. McDade, TP, Perugini, RA, Vittimberga, FJ, Callery, MP.  “TNF-a-induced apoptosis in human pancreatic cancer cells is enhanced by salicylates.” Poster presentation at the New England Cancer Society 1998 Annual Fall Program/112th Meeting, Worcester, MA  November 13-15, 1998. Perugini, RA, McDade, TP, Vittimberga, FJ, Callery, MP.  “Salicylate perpetuates G1 cell cycle arrest in human pancreatic cancer.” Poster presentation at the New England Cancer Society 1998 Annual Fall Program/112th Meeting, Worcester, MA  November 13-15, 1998. Perugini, RA, Swanson, RS, Lancey, RA.  “Cardiac surgery in patients with malignancy.” Poster presentation at the New England Cancer Society 1998 Annual Fall Program/112th Meeting, Worcester, MA  November 13-15, 1998. McDade, TP, Perugini, RA, Vittimberga, FJ, Carrigan, RC, Callery, MP.  “Ubiquitin proteasome inhibition enhances apoptosis of human pancreatic cancer cells.” Oral presentation at the Society of University Surgeons 60th Annual Meeting, New Orleans, LA  February 11-13, 1999. Perugini, RA, McDade, TP, Vittimberga, FJ, Callery, MP.  “Sodium salicylate decreases cyclin D1 expression and induces G1 cell cycle arrest in human pancreatic cancer cells.” Oral presentation at the Society for Surgery of the Alimentary Tract 40th Annual Meeting, Orlando, FL May 16-19, 1999 and at the SSAT/Ross Laboratories Residents and Fellows Research Conference, Howey-in-the-Hills, FL May 15, 1999. Kim, R, Vittimberga, FJ, Perugini, RA, McDade, TP, Nolan, BW, Bankey, PE, Chari, RS.  “Hypo-osmotic cell swelling activates NF-kB in primary rat hepatocytes:  implications in ischemia reperfusion injury in the transplanted liver.”  Poster presentation at the American Society for Transplant Surgery, May 19-21, 1999  Vittimberga, FJ, Nolan, BW, Perugini, RA, Spector, L, Callery, MP.  “Laparoscopy alters MAP-kinase activation in hepatic Kupffer cells.”  Poster presentation at the Society of American Gastrointestinal Endoscopic Surgeons Scientific Session, San Antonio, TX, March 24-27, 1999. Vittimberga, FJ, Nolan, BW, Perugini, RA, Spector, L, Callery, MP.  “Effects of laparoscopic surgery on Kupffer cell cytokine production.”  Oral presentation at the Society of American Gastrointestinal Endoscopic Surgeons Scientific Session, San Antonio, TX, March 24-27, 1999. Perugini, RA, McDade, TP, Vittimberga, FJ, Callery, MP.  “Human pancreatic cancer cell proliferation is phosphatidylinositol 3-kinase (PI3K)-dependent.”  Oral presentation at the Plenary Session of the Association for Academic Surgery, Philadelphia, PA, November 16-18, 2000. Kim, R, Perugini, RA, Chari, RS.  “Hypo-osmotic stress activates p70 S6 kinase independent of protein kinase B in primary rat hepatocytes:  implications in cell salvage.”  Submitted to American Association for the Study of Liver Disease, 2000. Ricciardi, R, Kim, R, McDade, TP, Perugini, RA, Veal, TM, Quarfordt, SH, Chari, RS, Meyers, WC.  “NF-kB expression during cold ischemia correlates with post reperfusion graft function.”  Oral presentation at the Association for Academic Surgery, Philadelphia, PA, November 16-18, 2000. Ricciardi, R, Schaffer, BK, Perugini, RA, Anwaruddin, S, Quarfordt, SH, Chari, RS, Meyers, WC.  “HIF-1a expression during cold ischemia correlates with post reperfusion hapatic graft function.”  Oral presentation at the Society of University Surgeons Resident’s Forum, February, 2000.  Perugini, RA, Kercher, K, Baker, SA, Meyers, WC, Litwin, DEM, Kelly, JJ.  “Laparoscopic Roux-en Y gastric bypass is feasible in super-obese patients:  lessons learned from our initial experience.” Oral presentation at the 81rst annual meeting of the New England Surgical Society, Boston, MA, October, 2000.